Cochrane Database Syst Rev: Chlorhexidine mouthrinse as an adjunctive treatment for gingival health.

2017 Mar 31;3:CD008676. doi: 10.1002/14651858.CD008676.pub2.

Chlorhexidine mouthrinse as an adjunctive treatment for gingival health.

Main findings:
1. There is high-quality evidence from studies that reported the Löe and Silness Gingival Index of a reduction in gingivitis in individuals with mild gingival inflammation on average (mean score of 1 on the 0 to 3 GI scale) that was not considered to be clinically relevant.
2. There is high-quality evidence of a large reduction in dental plaque with chlorhexidine mouthrinse used as an adjunct to mechanical oral hygiene procedures for 4 to 6 weeks and 6 months.
3. There is no evidence that one concentration of chlorhexidine rinse is more effective than another.
4.There is insufficient evidence to determine the reduction in gingivitis associated with chlorhexidine mouthrinse use in individuals with mean GI scores of 1.1 to 3 indicating moderate or severe levels of gingival inflammation.
5.Rinsing with chlorhexidine mouthrinse for 4 weeks or longer causes extrinsic tooth staining. In addition, other adverse effects such as calculus build up, transient taste disturbance and effects on the oral mucosa were reported in the included studies.
Link: https://www.ncbi.nlm.nih.gov/pubmed/28362061

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