Single shot of 17D vaccine may not confer life-long protection against yellow fever.

. 2018 Feb; 113(2): 135–137.
Published online 2017 Nov 27. doi:  10.1590/0074-02760170347
PMCID: PMC5722260
Single shot of 17D vaccine may not confer life-long protection against yellow fever

The yellow fever (YF) vaccine has been used since the 1930s to prevent YF, which is a severe infectious disease caused by the yellow fever virus (YFV), and mainly transmitted by Culicidae mosquitoes from the genera Aedes and Haemagogus . Until 2013, the World Health Organization (WHO) recommended the administration of a vaccine dose every ten years. A new recommendation of a single vaccine dose to confer life-long protection against YFV infection has since been established. Recent evidence published elsewhere suggests that at least a second dose is needed to fully protect against YF disease. Here, we discuss the feasibility of administering multiple doses, the necessity for a new and modern vaccine, and recommend that the WHO conveys a meeting to discuss YFV vaccination strategies for people living in or travelling to endemic areas.

Link to the full article:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722260/#B7

 

 

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